WebMar 1, 2024 · Anti-phospholipase A2 receptor autoantibody was identified using human glomerular extract ().It reacts to the denatured and nonreduced PLA2R on Western blot, … Web(A) The cartoon shows the constructs with the 1–3 construct or CTLD1 domain deletion and a full-length PLA 2 R with an introduced thrombin digestion site between CTLD1 and CTLD2 domains. Deleted ...
Clinical Relevance of Domain-Specific Phospholipase A
Web6 serum samples were identified to react strongly to the region of CysR-FnII-CTLD1-3, but weakly to the region of CysR-FnII-CTLD1 when diluted at 1:5000 on the Western-blot. 42 … WebAnti-PLA2R antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the 12-6-5 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mice immunized with recombinant fragment of human PLA2R corresponding to extracellular sequence NC3. Secretory phospholipase A2 receptor (PLA2R) is 180 kDa and is a type I ... orange county ca tax lien sale
THSD7A staining of membranous glomerulopathy in clinical practice ...
WebA gene encoding a novel type of receptor protein-tyrosine kinase was identified in Hydra vulgaris. The extracellular portion of this receptor (which we have namedSweet Tooth) contains four C-type lectin-like domains (CTLDs). Comparison of the sequences of these domains with the sequences of the carbohydrate recognition domains of various … WebSep 1, 2024 · M-type phospholipase A2 receptor (PLA2R) is a member of the mannose receptor family. Recent evidence shows that PLA2R is a major autoantigen causing idiopathic membranous nephropathy (IMN), which is an autoimmune disease and one of the most common causes for nephrotic syndrome in adults. The epitope … WebDownload scientific diagram Validation of three epitope-specific ELISAs using CysR, CTLD1 and CTLD7 domains and reactivity of PLA2R1-positive patients with iMN. (A) ELISAs were validated with ... iphone nn5 car charger