High affinity copper uptake protein 1-like

Web25 de set. de 2024 · Abstract Copper is crucial for carrying out normal physiological functions in all higher life forms. Copper Transporter 1 (CTR1) is the high-affinity copper importer found in all eukaryotic organisms. The copper transporter family primarily comprises ~ six members (CTR1-6) and the related members share high sequence … Web21 de abr. de 2011 · COPT7 alone could mediate a high-affinity Cu uptake in the yeast mutant. None of the seven COPTs alone or in cooperation could complement the phenotypes of S. cerevisiae mutants that lacked the transporter genes either for iron uptake or for zinc uptake.

Showing Protein High affinity copper uptake protein 1 …

WebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function Web11 de abr. de 2024 · Several lines of evidence presented here strongly suggest that the first histidine (His43) upstream from TMD1 is absolutely required for the copper transport activity of COPT1 protein. Firstly, deletion of 43 residues, but not 41 residues, of the extracellular N-terminus, completely blocked high affinity copper uptake of COPT1. cryptococcus neoformans penicillin resistant https://amazeswedding.com

RCSB PDB - 6M97: Crystal structure of the high-affinity copper ...

WebHigh affinity copper uptake protein 1: Synonyms: Copper transporter 1; Solute carrier family 31 member 1; hCTR1; Gene Name: SLC31A1: Protein Type: Transporter: Biological Properties; ... structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture. Web15 de abr. de 2024 · Protein target information for High affinity copper uptake protein 1 (pig). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. WebCopper is an essential cofactor for key processes in plants, but it exerts harmful effects when in excess. Previous work has shown that the Arabidopsis (Arabidopsis thaliana) COPT1 high-affinity copper transport protein participates in … cryptococcus neoformans pcr

The SLC31 (Ctr) copper transporter family SpringerLink

Category:High affinity copper uptake protein 1 (pig) - PubChem

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High affinity copper uptake protein 1-like

O15431 - UniProt

http://varidt.idrblab.net/ Webencode a high affinity copper uptake process and was found to be 29% identical at the primary structure level with Ctr1 from yeast. The human protein was, however, substantially smaller than the yeast protein, being composed of 190 amino acids as compared with 406 amino acids (see Fig. 1). hCTR1 is on the

High affinity copper uptake protein 1-like

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WebChemokines and chemokine receptors have been recognized as critical signal components that maintain the physiological functions of various cells, particularly the immune cells. The signals of chemokines/chemokine receptors guide various leukocytes to respond to inflammatory reactions and infectious agents. Many chemokine receptors play supportive … WebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at …

WebBecause copper uptake at the cell membrane is a crucial step in copper acquisition, yeast genes encoding the high affinity copper transport proteins are tightly regulated in response to copper levels to ensure … Web9 de jun. de 2024 · ATP7A, copper-transporting ATPase 1; ATP7B, copper-transporting ATPase 2; ATOX1, copper transport protein ATOX1; BBB, blood-brain barrier; CCS, copper chaperone for superoxide dismutase; CNS, central nervous system; CP, ceruloplasmin; CTR1, high affinity copper uptake protein 1; CTR2, probable low …

WebCopper uptake transmembrane transporter activity Specific Function High-affinity, saturable copper transporter involved in dietary copper uptake. Pfam Domain Function. … WebProtein High affinity copper uptake protein 1 Gene SLC31A1 Source organism Homo sapiens (Human) go to search UniProt O15431 go to UniProt Experimental structures 3 …

Web1 de abr. de 2002 · Copper uptake High-affinity copper transport proteins Physiological and biochemical studies many years ago suggested the presence of at least two independent activities responsible for copper uptake in eukaryotic cells, of distinct affinities and capacities for copper [6].

Web8 de abr. de 2024 · Water soluble CB[7]-PEG conjugate still maintains a high affinity for the N-terminal Phe of insulin (K d = 2.1 ± 0.3 μM) like unmodified CB[7]. The pendant PEG chain of at least 30 kDa in CB[7]-PEG conjugate didn't alter the affinity due to steric hindrance of CB[7] for insulin. durham bankruptcy attorneyWebHigh affinity copper uptake protein 1 Alternative names Copper transporter 1 ( rCTR1) Liver regeneration-related protein LRRGT00200 Solute carrier family 31 member 1 … durham bar association ncWeb11 de abr. de 2024 · Thiamine is metabolized into the coenzyme thiamine diphosphate (ThDP). Interrupting thiamine utilization leads to disease states. Oxythiamine, a thiamine analogue, is metabolized into oxythiamine diphosphate (OxThDP), which inhibits ThDP-dependent enzymes. Oxythiamine has been used to validate thiamine utilization as an … durham b and bdurham bed and furniture groupWebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 … durham beamish \u0026 holy islandWebProtein target information for High affinity copper uptake protein 1 (house mouse). Find diseases associated with this biological target and compounds tested against it in … durham baseball recreationWeb30 de mar. de 2024 · Functional assays revealed that it stimulates the initial rate of radiolabeled copper uptake. CTR1 transports copper with high affinity in a time-dependent and saturable manner and is copper-specific. Transport is an energy-independent process and is stimulated by extracellular acidic pH and high K+ … durham bathroom vanity