Irf1 molecular weight

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August undefined, 2024

WebIRF1 Antibodies. Antibodies that detect IRF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and Flow Cytometry. These antibodies target IRF1 in Human, Mouse and Rat samples. Our IRF1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed ... WebDescription Product name Recombinant Human IRF1 protein (His tag) Purity > 90 % SDS-PAGE. NULL Endotoxin level < 1.000 Eu/µg Expression system Escherichia coli Accession …

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WebMar 21, 2024 · IRF1 (Interferon Regulatory Factor 1) is a Protein Coding gene. Diseases associated with IRF1 include Lung Cancer and Gastric Cancer. Among its related pathways are Bacterial infections in CF airways and Overview of interferons-mediated signaling … HBB (Hemoglobin Subunit Beta) is a Protein Coding gene. Diseases associated with … Gene Ontology (GO) - Molecular Function for MET Gene. GO ID Qualified GO term … VCAM1 (Vascular Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases … Complete information for IWS1 gene (Protein Coding), Interacts With SUPT6H, … PHGDH (Phosphoglycerate Dehydrogenase) is a Protein Coding gene. Diseases … CCL2 (C-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases … IFITM1 (Interferon Induced Transmembrane Protein 1) is a Protein Coding gene. … CCL19 (C-C Motif Chemokine Ligand 19) is a Protein Coding gene. Diseases … IGFBP7 (Insulin Like Growth Factor Binding Protein 7) is a Protein Coding gene. … CDKN1B (Cyclin Dependent Kinase Inhibitor 1B) is a Protein Coding gene. Diseases … WebJan 15, 2024 · IRF1 are marked using red, and HSPA4, PDLIM4, and VDAC1 are illustrated in dark, common and light yellow, respectively; TCF7, SKP1, and PPP2CA appear as dark, … hillside roofing \u0026 gutters

IRF1 is critical for the TNF-driven interferon response in

WebJan 15, 2024 · Interferon regulatory factor 1 (IRF1) is an important regulator in controlling the transcription of type I interferon genes, and its functions have been well-characterized in mammals, birds and fish. However, little information is available regarding the function of amphibian IRF1. WebDec 1, 2024 · LcIRF2, LcIRF5, LcIRF6, LcIRF10, and LcIRF11 have ORF of 954, 1476, 1473, 1206, and 792 bp, encoding 318, 492, 491, 402, and 264 aa, with a predicted molecular … WebPredicted molecular weight. 32.27 kDa . Stability and Storage. Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt. ... IRF1. Species. Human . Shipping. In general, proteins are provided as lyophilized powder/frozen liquid. They ... smart life plugs offline

IRF1 - phosphosite.org

WebWhen using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain … WebApr 4, 2024 · IRF1 is involved in TLR- and cytokine-mediated signaling in human myometrium. 5AZ had a protective effect after MI by potentiation of IRF1 sumoylation and … smart life performanceWebApr 10, 2024 · The predicted theoretical isoelectric point of pIgR amino acid sequence is 5.92, and theoretical molecular weight is 37.48 kDa, and the first 19 amino acids are signal peptides. It is predicted that there may be an N-linked glycosylation site (N 34 LTV) in the extracellular domain (Fig. 1). Download : Download high-res image (4MB) hillside roofing allenwood pa

"WebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. ... Consistently, molecular function enrichment … " - Irf1 molecular weight

Irf1 molecular weight

Molecular characterization of the interferon regulatory factor (IRF ...

WebMar 29, 2024 · IRF1 and IRF2 also appear to be important in regulating DC subset development— Irf −/− mice show a loss of splenic and epidermal DCs (due to augmented type I IFN signaling) ( 109, 110) whereas Irf1−/− exhibit an increase in pDCs and a decrease in CD8 + DCs in mice, along with an increase of IL-10 and TGF-β ( 111 ). WebNov 26, 2024 · As expected, extracellular high molecular weight poly(I:C) did not induce Mda5 expression ... Twenty-four hours after transfection, the cells were stimulated for 3 h with IFN-α or LPS and Irf1 expression was determined by qPCR (n = 4) ...

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WebJun 30, 2016 · Besides CCL2, the transcription factor IRF1, which has proapoptotic activities was significantly upregulated after IL6/sgp80 or OSM stimulation. qRT-PCR revealed a rapid (within 2 hours) and strong (10- to 12-fold) induction of IRF1 mRNA after OSM or IL6/sgp80 stimulation in HeLa and SW756 cells (Fig. 6A; P <0.0001). WebJan 15, 2024 · Molecular and functional characterization of interferon regulatory factor 1 (IRF1) ... 10 μg/g body weight] for 3 h, whose spleen and kidney were used for the extraction of total RNA by using Trizol Reagent (Invitrogen). The first-strand cDNA was synthesized from above total RNA and served as template to amplify ORF sequence of Xt-IRF1 by PCR ...

http://antibodysystem.com/product/3227.html WebDec 27, 2024 · Results: IRF1 was identified as a novel TF that suppresses KPNA2 gene expression. We observed that IRF1 expression was lower in cancerous tissues than in normal lung tissues and that its low expression was correlated with poor prognosis in …

WebObjectives: Although it has been reported that Interferon regulatory factor 1 (IRF1) inhibits Mycobacterium tuberculosis (Mtb) infection via inducible nitric oxide synthase (iNOS) in mice, how it counteracts with mycobacterial infection in human remains largely obscure. WebWestern blot analysis of HeLa cells, untreated or treated with Human Interferon-γ (hIFN-γ) #8901 (100 ng/ml, 4 hr), using IRF-1 (D5E4) XP ® Rabbit mAb. Western blot analysis of …

WebApr 4, 2024 · IRF-1 is an important signaling protein in the interferon pathway. It not only activates gene expression as a transcription factor, but may perpetuate disease by leading to a dysregulated epigenome. Data suggest that interferon regulatory factors 1 and 2 (IRF1 and IRF2) may serve as potential targets of therapy.

WebDec 1, 2024 · The predicted molecular weight of the Cf IRF1 protein was approximately 40 kDa. Using the SMART program and NCBI conserved domain search program, the N-terminus of the Cf IRF1 protein was predicted to encode an IRF1 domain, similar to IRF1 family proteins of other species ( Fig. 2 A ). Download : Download high-res image (2MB) hillside roofing jersey shoreWebMay 5, 2014 · Cellular & Molecular Immunology - K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascade ... Adding weight to this was the observation that SKI-1, ... hillside roller coaster smart life nfcWebDisruption of this signaling pathway by deletion of Irf1 or Stat1 protects mouse macrophages from TNF-α- and IFN-γ- induced cell death, as well as induced holopsia deletion in the absence of Irf1. Similarly, Stat1-/- mice were protected from TNF- and IFN-γ- induced death. Figure 4. TNF-α and IFN-γ induce JAK/STAT1/IRF1 signaling and PANoptosis hillside rtcWebUse a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 36 kDa. ICC Use a concentration of 0.5 - 1 µg/ml. IHC-P ... Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer … smart life on pcWebIRF1-regulated gene expression equipped low-grade PDAC cells with distinctive properties related to antigen presentation and processing as well as responsiveness to IFN stimulation. smart life parkWebJun 19, 2024 · This observation was further corroborated by molecular studies showing increased percentages of IL-17A/IFN-γ-producing CD4 + T cells in the central nervous … smart life pro windows